Alendronic Acid

UNDER REVIEW (April 2017)

Mechanism of Action:

A bisphosphonate drug. Bisphosphonates are analogs of a naturally occurring compound pyrophosphate which are adsorbed onto hydroxyapatite crystals in bone, slowing both their rate of growth and dissolution, and therefore reducing the rate of bone turnover. They reduce bone resorption by osteoclasts, hinder recruitment of osteoclasts, and stimulate osteoblasts to produce an inhibitor of osteoclast formation.

Lecture and CAL materials: