• Gastric protection during therapy with NSAIDs
  • Therapeutic abortion (with the anti-progestogen agent mifepristone and usually methotrexate)
  • Can be used in induction of labour

Mechanism of Action:

Prostaglandin E (EP) receptor agonist. EP receptors are seven-transmembrane G-protein-coupled receptors.

Lecture and CAL materials: (under review)


Mechanism of Action:

Macrolide antibiotic. Reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This inhibits both T-lymphocyte signal transduction and IL-2 transcription.

Lecture and CAL material: