Indications:
- Cutaneous Candidiasis (Thrush) and other cutaneous fungal (‘dermatophyte’) infections including athlete’s foot.
Mechanism of Action:
Clotrimazole is an antifungal drug (imidazole) that damages the fungal cell wall and alters the permeability. It also inhibits the activity of intracellular enzymes, leading to a buildup of toxic concentrations of hydrogen peroxide within the fungal cell, causing death of the cell. It is used topically; systemic absorption is minimal.
Lecture and CAL materials: (under review)
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