Drug Classification: Premature Labour

UNDER REVIEW (September 2016)

Mechanism of Action:

Selective short-acting beta-2 adrenoceptor agonist i.e. has minimal effect on beta-1 adrenoceptors and is inactive at alpha-adrenoceptors. Actions of beta-2 adrenoceptor (a seven-transmembrane G-protein-coupled receptor) include: bronchodilation, vasodilation, smooth muscle relaxation. Its actions are achieved through activation of adenylate cyclase, which causes the formation of cylic AMP (second messenger) from ATP.

Lecture and CAL materials:

• Lecture: Drugs and the Sympathetic Nervous System
• Lecture: Drugs affecting the respiratory system
• Lecture:
• CAL: G Proteins
• CAL: Pharmacology of Asthma

UNDER REVIEW (September 2016)

Mechanism of Action:

Selective short-acting beta-2 adrenoceptor agonist i.e. has minimal effect on beta-1 adrenoceptors and is inactive at alpha-adrenoceptors. Actions of beta-2 adrenoceptor (a seven-transmembrane G-protein-coupled receptor) include: bronchodilation, vasodilation, smooth muscle relaxation. Its actions are achieved through activation of adenylate cyclase, which causes the formation of cylic AMP (second messenger) from ATP.

Lecture and CAL materials:

• Lecture: Drugs and the Sympathetic Nervous System
• Lecture:
• CAL: G Proteins